Signal Detection of Adverse Drug Reactions

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منابع مشابه

Toward multimodal signal detection of adverse drug reactions

OBJECTIVE Improving mechanisms to detect adverse drug reactions (ADRs) is key to strengthening post-marketing drug safety surveillance. Signal detection is presently unimodal, relying on a single information source. Multimodal signal detection is based on jointly analyzing multiple information sources. Building on, and expanding the work done in prior studies, the aim of the article is to furth...

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adverse drug reactions Detection , verification , and quantification

http://bmj.com/cgi/content/full/329/7456/44 Updated information and services can be found at: These include: Data supplement http://bmj.com/cgi/content/full/329/7456/44/DC1 "Systems for drug safety research and references" References http://bmj.com/cgi/content/full/329/7456/44#otherarticles 3 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/329/7456/44#...

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We investigated factors affecting the timing of signal detection by comparing variations in reporting time of known and unknown ADRs after initial drug release in the USA. Data on adverse event reactions (AERs) submitted to U.S. FDA was used. Six ADRs associated with 6 drugs (rosuvastatin, aripiprazole, teriparatide, telithromycin, exenatide, varenicline) were investigated: Changes in the propo...

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ژورنال

عنوان ژورنال: Japanese Journal of Pharmacoepidemiology/Yakuzai ekigaku

سال: 2009

ISSN: 1342-0445,1882-790X

DOI: 10.3820/jjpe.14.27